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Procedure of the Month

This is the case of a 68 year-old male suffering from severe back pain for 3 months. Patient failed conservative treatment with high doses of analgesics. MRI was performed, as shown in Figure 1 below. This T2-weighted image clearly revealed evidence of acute fracture with bone marrow edema at the L1 level. Which choice do you think best describes the patient's treatment options (click on the x-ray below to take the multiple choice/guess test)?

Figure 1: Preoperative T2-weighted sagittal MRI showed evidence of bone marrow edema indicative of acute fracture at the L1 level (arrow).

Case review and x-rays courtesy of
Dr. Bassem A Georgy.
Interventional Radiologist Valley Radiology Consultants Assistant Clinical Professor University of California, San Diego

SPONSORED BY:


Procedure of the Month Sponsored by DePuy Spine, Inc.


 

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Large Joints News

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Replace or Fuse? Can’t Decide?
By Dev Joshi (posted April 29, 2008)
An upcoming paper titled “Controversy of Total Ankle Arthroplasty” says the answer should increasingly be “replace.” Certainly as an outpatient procedure and with new technologies like Wright Medical’s new INBONE system, replacement/arthroplasty is on the rise. Using PearlDiver data we map out this very important market.

Put on Your Futuristic Headgear: Immersion Medical and GMV Sign Agreement for Reality Arthroscopy Simulation System
By Elizabeth Hofheinz (posted April 25, 2008)
So much for skiddishness about minimally invasive surgery…Immersion Corporation, a touch feedback technology firm, and GMV, an engineering firm, have announced that Immersion Medical, a wholly owned subsidiary of Immersion, and GMV have signed an agreement whereby Immersion Medical will market and sell GMV's insightArthroVR® virtual reality arthroscopy surgical simulator in most countries around the world.

Anesiva’s Adlea™ in Phase 3 Clinical Trial
By Elizabeth Hofheinz (posted April 17, 2008)
Keith knows knees. And Anesiva knows Adlea™. The company is announcing that it has embarked upon a Phase 3 study to evaluate Adlea in patients after total knee replacement surgery.

Log On and the Doctor Is In: Elsevier Expands Procedures Consult™
By Elizabeth Hofheinz (posted April 17, 2008)
Work on a keyboard before working on a patient! The medical publishing experts at Elsevier have announced that they have added three new modules to Procedures Consult™ in orthopedics, anesthesia and emergency medicine.

Geriatric Orthopedic Surgery – It’s the future, baby!
By Billie Young (posted April 8, 2008)
The number of patients over 65 years of age is increasing 10 times faster than those under 65. Is your practice ready? The average geriatric patient has 1.8x the complications of the non-geriatric patient. Medicare is now paying a small bounty to those surgeons willing to track comorbidities. Read how one orthopedist has made geriatric orthopedics her primary focus.

Anticoagulant Use After Joint Replacement May Contribute to Higher Mortality
By Elizabeth Hofheinz (posted April 3, 2008)
According to eBiologyNews, a recent study has found that the use of anticoagulants to prevent blockage in pulmonary artery after joint replacement operations may actually lead to more deaths among patients taking these drugs.

Cartilage Repair Leader TiGenix Updates Clinical Trial Results
By Robin Young (posted March 26, 2008)
As part of the company’s year-end review, management updated results from its large clinical trial of the ChondroCelect® cartilage repair product. TiGenix conducted a Phase III, pivotal clinical trial of a cartilage repair product for the knee.

Rheumatoid Arthritis Treatment Approval Sought
By Robin Young (posted March 24, 2008)
Centocor, Inc. and Schering-Plough Corporation announced that they have, collaboratively, submitted a Marketing Authorization Application (MAA) to the European Medicines Agency (EMEA) requesting approval of golimumab (CNTO 148) as a monthly subcutaneous treatment for adults with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.

UConn Researchers Tackle Arthritis With Stem Cells
By Robin Young (posted March 24, 2008)
A team of researchers from the University of Connecticut say that they have been able to turn human embryonic stem cells into the type of cells that make up cartilage. If confirmed by other labs, this work could add significantly to the understanding of the cellular processes underlying cartilage regeneration and an eventual cellular treatment for osteoarthritis.

AAOS Through a Mega-Buyer’s Eyes
By Robin Young (posted March 18, 2008)
Maryann, Scott, Brian, and Rudy buy orthopedic products for roughly half the surgeries in the United States. They were arguably the four most important buyers at this year’s AAOS exhibit floor. Yet few suppliers or surgeons realize who these buyers are or how important they are. Isn’t it time you knew? If so, read on.

S&N Launches R3™ Acetabular System
By Elizabeth Hofheinz (posted March 14, 2008)
Smith & Nephew’s Orthopaedic Reconstruction business today announced the global launch of the R3™ Acetabular System, an advanced multi-bearing acetabular cup system used in total hip replacement procedures.

Smith & Nephew Unveils New Suture Anchor
By Elizabeth Hofheinz (posted March 14, 2008)
It may sound like a dinosaur, but it’s the latest technology in sutures. Smith & Nephew's Endoscopy Division has announced the launch of the BIORAPTOR™ 2.3 PK Suture Anchor for repair of instability in the hip or shoulder joint.

ConforMIS, Inc. Introduces the First Patient-Specific Unicompartmental Knee Resurfacing Implant on the Market
By Elizabeth Hofheinz (posted March 3, 2008)
ConforMIS has announced the launch of the iUni™ unicompartmental knee resurfacing implant and its accompanying iJig™ disposable instrumentation. The iUni, to be used for osteoarthritis of the knee, is a unicompartmental resurfacing implant designed for patients whose arthritic damage is isolated to either the medial or lateral compartments of the knee, with little to no damage present in the other compartments.

The Good News About Bad News
By Scott Ellison (posted February 11, 2008)
Hypertension affects 16% of the U.S. population. But how does it affect patients undergoing hip or knee replacement surgery? Using the PearlDiver database of over 100 million patient records we turn up a surprising answer. Certain complication rates are lower for patients with high blood pressure than for similar patients. Curious to learn more? Read on.

ConforMIS Products Approved in All European Union Markets
By Elizabeth Hofheinz (posted February 22, 2008)
ConforMIS, Inc., a privately held company that develops and commercializes minimally invasive medical devices for the treatment of osteoarthritis and joint damage, announced that it has received CE Mark approvals for both the iUni™ uni-compartmental resurfacing device and the iJig™ instrument system for use with the iUni on December 3, 2007.

New Non-invasive Imaging Method for Diagnosing Osteoarthritis
By Elizabeth Hofheinz (posted February 15, 2008)
Molecular vision! New York University and Tel Aviv University researchers have developed a non-invasive imaging method that can be used to diagnose and monitor a number of diseases, including osteoarthritis and intervertebral disc degeneration (in their early stages).

Corin Reports 28% Sales Jump for 2007
By Robin Young (posted February 14, 2008)
Corin Group PLC, the Britain-based orthopedic implant manufacturer, reported that sales for the year ended December 31, 2007, are expected to have risen a strong 28% to £36.5 million (about U.S. $71.2 million).

Wright Adds PROFEMUR® Stem Designs and Less-Invasive Surgical Technique
By Elizabeth Hofheinz (posted February 8, 2008)
If there were an ortho-catwalk, Wright Medical would be shaking its hips. New from Wright in ’08 is a cemented modular neck hip implant (the company’s first), a wedged stem for revision hip replacement, as well as a new technique for total hip arthroplasty.

ACL Reconstruction and the Double-Bundle Bungle?
By Scott Ellison (posted February 5, 2008)
Is there truly a benefit to the double-bundle anterior cruciate ligament (ACL) procedure? Or is the procedure in fact a bungle, inadequate in comparison to the standard ACL? Analyzing thousands of procedures in the PearlDiver database, we answer the question.

Entelos and UCB Pharma Sign Agreement on Rheumatoid Arthritis
By Elizabeth Hofheinz (posted January 24, 2008)
How “virtual patients” will make real change a possibility. Life sciences company Entelos, Inc. has announced that it has signed an agreement with UCB Pharma S.A. to conduct in silico research in the field of rheumatoid arthritis (RA) using the Entelos® Rheumatoid Arthritis PhysioLab® platform.

   

News Shorts
Complete Issue - PDF Past Issues

Scient'x Doubles 510(k) Clearance With DUO™ Dynamic Stabilization System
First there was one level...now there are two. Scient'x announced on May 6 that it had received FDA 510(k) clearance to market its new Isobar DUO™ Dynamic Stabilization System.

Alphatec Ponies Up $11 Million Settlement for ‘678 Patent
"Alphatec can now achieve some certainty." That's what Alphatec's President and CEO, Dirk Kuyper, told us at the SAS annual meeting in Miami Beach. He was referring to his company's announcement that its 2006 lawsuit with Biedermann and DePuy over the ‘678 pedicle screw patent is settled.

Abbott Spine’s Universal Clamp™ Now Available Stateside
The Universal Clamp™ spinal fixation system, developed by Abbott Spine, may now be enjoyed by Americans. The implant, which has been available in Europe for over a year, can be used to correct a wide variety of complex spinal pathologies including sagittal and coronal malalignment, as well as degenerative conditions of the thoracolumbar spine.

Facet Solutions, Inc. Completes Combination Facet Joint and Disc Replacement Study
It’s the motion in Miami…Facet Solutions, Inc. is announcing the successful completion of a scientific evaluation for a total joint reconstruction in the lumbar spine. The study evaluated the combination of Facet Solutions’ Anatomic Facet Replacement System (AFRS™) with a semi-constrained disc replacement device in a finite element model.

Biologic Bummer for Stryker in Beantown
Stryker's stock stopped trading for 16 minutes before resuming on Friday, May 2. The reason was because Stryker was about to announce that its Biotech division, in the Boston suburb of Hopkinton, had received a warning letter from the U.S. Food and Drug Administration (FDA) related to quality systems and compliance issues.

MAKO’s Robot Zaps 1st Quarter Expectations
MAKO Surgical Corp. reported 2008 first quarter revenues of $500,000. Analysts had expected revenues of only $300,000. The company markets its Tactile Guidance System™ (TGS™), an advanced robotic-arm solution, and its implants for minimally invasive orthopedic knee procedures, known as MAKOplasty®.

Shake Up at Medtronic Sofamor Danek
We were frankly surprised as were many people both inside and outside the company to hear of Pete Wehrly’s sudden departure from Medtronic Sofamor Danek day before yesterday. Mr. Wehrly, 49, was the President of Medtronic Sofamor Danek and the abruptness of his departure followed by Medtronic’s extreme caution in commenting adds additional mystery to the circumstances of Pete’s leaving.

DePuy Puts 3 Million Sq. Ft. to Work in China
DePuy products have gone into production in Suzhou, China. Tradingmarkets.com reported on April 25 that Johnson & Johnson Medical (DePuy-Suzhou) Ltd. has started operations at its first Chinese facility to produce medical equipment in the Suzhou Industrial Park in eastern China.

Smith & Nephew Endoscopy Launches FOOTPRINT PK Suture
Just try to follow in their footsteps! Smith & Nephew's Endoscopy Division has announced the launch of the FOOTPRINT PK Suture Anchor, a system used to attach rotator cuff tissue to bone in the shoulder.

Put on Your Futuristic Headgear: Immersion Medical and GMV Sign Agreement for Reality Arthroscopy Simulation System
So much for skiddishness about minimally invasive surgery…Immersion Corporation, a touch feedback technology firm, and GMV, an engineering firm, have announced that Immersion Medical, a wholly owned subsidiary of Immersion, and GMV have signed an agreement whereby Immersion Medical will market and sell GMV's insightArthroVR® virtual reality arthroscopy surgical simulator in most countries around the world.

Zimmer Revenues On Target for First Quarter. Disappoints Investors
Zimmer reported first quarter 2008 revenues (constant currency) on April 24. Total Revenues: up 6.2% to $1.06 billion. The company also announced a $1.25 billion stock repurchasing program and reaffirmed earlier guidance for the year of 6%–7% revenue growth (in constant currency).

Physician Disciplinary Actions Decline 22% Since 2004
With the current hyper-vigilant focus on surgeon and industry relationships, it begs the question: Are disciplinary actions against physicians increasing or decreasing?

Frost & Sullivan Shines Light on Raymedica
Feelin’ hot, hot, hot! Frost & Sullivan has named Raymedica, LLC, as winner of the 2008 Frost & Sullivan Hot Investment Opportunity Award.

NuVasive Revenues Break Expectations, Lukianov Waives HIPAA
The NuVasive Chairman and CEO waived all his HIPAA rights during a first quarter 2008 conference call with analysts on April 22 when asked about his own back surgery. He said he's doing very well after his two-level XLIF® procedure, thank you very much.

Good News for Lower Extremities: Archus Completes First Human Implant of TFAS-C™ System
They’ve come to a conclusion: Some patients can be done with fusion. The reconstructive implant aficionados at Archus Orthopedics, Inc. have announced the successful completion of the first human implant of their TFAS-C™ system, the newest addition to the company's product line for treating spinal stenosis.

DePuy Launches Spine System for Small-Stature Patients
DePuy Spine has launched a titanium and stainless steel hook, rod and screw system designed to treat complex spinal deformities in small-stature patients.

BoundaryMedical Inc. Launches Orthopedic Outcome Measurement Software
BoundaryMedical, Inc. may be able to streamline things. It has just introduced the new Outcome Enterprise™ Study Manager platform for measuring outcomes relating to orthopedic treatments.

People in the News

Jack Maertens Joins Theken Family of Companies as VP of Marketing

Mike McCarthy Joins Board at Facet Solutions

Patrick O’Donnell Joins Medical Capital Advisors

St. Francis Founder Joins Active Implants’ Board

Upcoming Conferences

SpineWeek
May 26 - 31, 2008 – Geneva, Switzerland

CMSA's 18th Annual Conference & Expo
June 17 - 20, 2008 – Orlando, Florida

 

   

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