Other Articles

How to Get the Surgeon’s Attention
Understanding relationship dynamics and having the chutzpah to put your best creative foot forward can garner you real success as a sales rep. Find out how to bring inventiveness to the sales process so as to attract and retain the surgeon’s attention.

Death Spiral
Since January, ReGen Biologic's stock has fallen from $0.95 per share to $0.04 per share. The number of shares outstanding is up 45% in 9 months. In one case, the company paid a $24,000 vendor bill with 68,572 shares of stock. Still, a couple of particularly savvy orthopedics investors have bought roughly 7% of the stock. Can ReGen survive?

Diving in to the Future
Since 1996 total knee procedures have risen 77% to 455,000 annually. A study presented at AAOS estimates that by 2030 that number grows to 3.48 million knee replacements a year! If infection rates continue to rise at current rates, however, that future will not be nearly as rosy for either patients or industry. Read on.

Selling Yourself: Career Advancement for Sales Reps
Are you considering becoming a distributor or do you plan to advance within a company? Either way, you need to be ready. You will want to know how to make product line choices, hire a sales force, and lead others, among other things.

Mission Unaccomplished: Are the Wheels Coming Off at the FDA?
The FDA is no longer able to fulfill its mission and its wheels are coming off. So says the FDA’s own Science Board in a scathing report. We looked under the hood of the report and here’s what we found.

“Back” to the Future Part II: Technology and the Vertebral Compression Fracture Market
In Part I, our inquiring analyst, Matt Menze, highlighted opportunities for spinal implant manufacturers in the vertebral compression fracture (VCF) market. Now he tackles the thorny issue of new and emerging VCF technologies. What’s on the horizon? Read on.

Second Careers for Orthopedic Surgeons
How should you plan for a change in focus later during your career? You may want to continue utilizing your research, managerial, or presentation skills. Find out what Drs. Ray Linovitz and Stephen Hochschuler have to say about how to stay involved in the field at any stage of one’s career.

Finally, Consolidation in the Allograft Industry
So, where’s Adam Smith’s enlightened self interest when you need it? For about the length of the average U.S. Presidency it’s been clear to anyone who could read an income statement that one important market sector was in need of consolidation. That sector is allograft. With RTI and Tutogen merging, it may finally be happening. Read on.

The Smell of Favoritism, Political Interference, and Back-Room Dealing Alleged in Ortho Deferred Prosecution Deal in Jersey
Amid charges of political favoritism, New Jersey Congressmen call for investigation of ortho deferred prosecution agreements. It’s Jersey and the fur’s flying, read about it here.

The Match Process: Let the Courtship Begin
In the first of three articles, two medical students describe their experiences of the residency match process. Learn their thoughts on interviewing, letters of recommendation, and of course, the pressure to match.

A New “Wave” of Extremity Treatment?
Addressing a market of more than a quarter of a million patients annually with a $5-8,000 treatment sounds like the next multi-billion market. FDA approved, but controversial. What is Extracorporeal Shock Wave Therapy and why should we care? Read on.

Avoiding the Perp Walk, or How to Keep the Justice Department From Knocking on Your Door
We’ve all seen the “Perp Walk” on TV. The defendant cuffed and trying to hide his or her face from the cameras. Will Justice Department and congressional investigations of industry and physician relationships result in a doc taking that walk? Read what a federal prosecutor says about avoiding that indignity.

At last week’s Orthopedic Trauma Association meeting in Boston, Aastrom Biosciences, Inc. released final results from its Phase I/II stem cell study for long bone non-union fractures. Matthew L. Jimenez, M.D. of the Illinois Bone and Joint Institute is lead investigator.

In the study, patients with non-union tibia, humerus or femur fractures that had failed to heal after one or more medical procedures showed an overall healing rate of 91% after one year. The study followed 36 eligible patients with severe long bone non-union fractures of the tibia, humerus or femur that had failed to heal with one or more (average of 1.75) prior medical procedures. The patients were enrolled in a multi-center, prospective, open-label clinical trial and treated with Aastrom’s stem cells.

The 33 patients with a full year’s follow up showed an overall healing rate of 91%, as determined by bone bridging observed with radiographic imaging or computed tomography. Final results showed healing success in 91% (21 of 23) of tibia fractures, 100% (3 of 3) of humerus fractures, and 86% (6 of 7) of femur fractures. No cell-related adverse events were reported.

In addition to bone regeneration, Aastrom is currently developing Tissue Repair Cell-based therapies for vascular, cardiac and neural tissue regeneration applications. The Company recently reported positive early data from a German study evaluating the use of Bone Repair Cells (BRCs) to treat patients suffering from osteonecrosis of the femoral head. Also reported were positive interim results from a German Phase I/II trial utilizing Vascular Repair Cells (VRCs) to treat diabetic patients with critical limb ischemia (CLI), the most severe form of peripheral arterial disease.